C‐kit Gene Abnormalities in Gastrointestinal Stromal Tumors (Tumors of Interstitial Cells of Cajal)

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the GI tract, and expresses KIT and CD34 in most cases. Gain‐of‐function mutation of the c‐kit proto‐oncogene has been described, but its significance in GIST has not yet been fully evaluated. Mutation in exon 11 of the c‐...

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Detalles Bibliográficos
Autores principales: Sakurai, Shinji, Fukasawa, Tomoki, Chong, Ja‐Mun, Tanaka, Akira, Fukayama, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926026/
https://www.ncbi.nlm.nih.gov/pubmed/10665649
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00715.x

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