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Apoptotic Changes Precede Mitochondrial Dysfunction in Red Cell‐type Pyruvate Kinase Mutant Mouse Erythroleukemia Cell Lines

Two erythroleukemia cell lines have been established from the splenic lesions of red blood celltype pyruvate kinase (R‐PK) activity‐deficient mice of CBA/N origin infected with a polycythemic strain of Friend leukemia virus complex (FVp). Ten to 30 % of the cells of these cell lines undergo apoptoti...

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Detalles Bibliográficos
Autores principales: Aisaki, Ken‐ichi, Kanno, Hitoshi, Oyaizu, Naoki, Hara, Yukichi, Miwa, Shiro, Ikawa1, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926040/
https://www.ncbi.nlm.nih.gov/pubmed/10189887
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00730.x