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Chemopreventive Effect of N‐(2‐Cyclohexyloxy‐4‐nitrophenyl)methane Sulfonamide (NS‐398), a Selective Cyclooxygenase‐2 Inhibitor, in Rat Colon Carcinogenesis Induced by Azoxymethane

Non‐steroidal anti‐inflammatory drugs (NSAIDs) such as sulindac and indomethacin inhibit colon carcinogenesis, and selective cyclooxygenase (COX)‐2 inhibitors are considered to be potential chemopreventive agents without the side effects of usual NSAIDs. We reported that NS‐398, N‐(2‐cyclohexyloxy‐4...

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Detalles Bibliográficos
Autores principales: Yoshimi, Naoki, Shimizu, Masahito, Matsunaga, Kengo, Yamada, Yasuhiro, Fujii, Keiko, Hara, Akira, Mori, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926081/
https://www.ncbi.nlm.nih.gov/pubmed/10363578
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00762.x

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