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PTEN/MMAC1 Mutations in Hepatocellular Carcinomas: Somatic Inactivation of Both Alleles in Tumors

Allelic loss of loci on chromosome 10q occurs frequently in hepatocellular carcinomas. Somatic mutations of the PTEN/MMAC1 gene on this chromosome at 10q23 were recently identified in sporadic cancers of the uterus, brain, prostate and breast. To investigate the potential role of PTEN/MMAC1 gene in...

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Detalles Bibliográficos
Autores principales:	Kawamura, Naoki, Nagai, Hisaki, Bando, Koichi, Koyama, Masaaki, Matsumoto, Satoshi, Tajiri, Takashi, Onda, Masahiko, Fujimoto, Jiro, Ueki, Takahiro, Konishi, Noboru, Shiba, Tadayoshi, Emi, Mitsuru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1999
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926086/ https://www.ncbi.nlm.nih.gov/pubmed/10363579 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00763.x

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