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Ex vivo Delivery of Suicide Genes into Melanoma Cells Using Epidermal Growth Factor Receptor‐specific Fab Immunogene

The Fab fragment of monoclonal antibody B4G7 against human epidermal growth factor (EGF) receptor was conjugated with cationic poly‐l‐lysine and the resulting conjugate was further complexed with reporter genes or therapeutic genes. This Fab/DNA complex was designated as “Fab immunogene”. The Fab im...

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Detalles Bibliográficos
Autores principales:	Ohtake, Yuichiro, Chen, Jiabing, Gamou, Shinobu, Takayanagi, Atsushi, Mashima, Yukihiko, Oguchi, Yoshihisa, Shimizu, Nobuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1999
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926092/ https://www.ncbi.nlm.nih.gov/pubmed/10363586 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00770.x

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