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Efficient Production of Adeno‐associated Virus Vectors Using Split‐type Helper Plasmids

Adeno‐associated virus (AAV) vectors are potentially useful vehicles for the delivery of therapeutic genes into human cells. To determine the optimal expression pattern of AAV proteins (Rep78, Rep68, Rep52, Rep40, and Cap proteins) for packaging the recombinant AAV genome, helper plasmids were split...

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Detalles Bibliográficos
Autores principales: Ogasawara, Yoji, Urabe, Masashi, Kogure, Katsuhiro, Kume, Akihiro, Colosi, Peter, Kurtzman, Gary J., Ozawa, Keiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926094/
https://www.ncbi.nlm.nih.gov/pubmed/10363588
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00772.x