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Increased 8‐Hydroxyguanine in DNA and Its Repair Activity in Hamster and Rat Lung after Intratracheal Instillation of Crocidolite Asbestos

Asbestos and man‐made‐mineral fibers are known to increase one type of oxidative DNA damage, 8‐hydroxyguanine (8‐OH‐Gua), in vitro. In this study, we analyzed the 8‐OH‐Gua level in DNA and its repair activity after a single intratracheal instillation of fibers (crocidolite or glass) or saline to Syr...

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Detalles Bibliográficos
Autores principales:	Yamaguchi, Raizo, Hirano, Takeshi, Ootsuyama, Yuko, Asami, Shinya, Tsurudome, Yosuke, Fukada, Shoko, Yamato, Hiroshi, Tsuda, Toru, Tanaka, Isamu, Kasai, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1999
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926107/ https://www.ncbi.nlm.nih.gov/pubmed/10391089 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00776.x

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