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Multidrug Resistance Phenotype in the RMS‐GR Human Rhabdomyosarcoma Cell Line Obtained after Polychemotherapy

Classical cytotoxic treatment of rhabdomyosarcoma (RMS), the most common soft tissue malignancy in children, is often accompanied by significant morbidity and poor response. Chemotherapy may induce multidrug resistance (MDR) associated with the expression of P‐glycoprotein, a drug efflux pump which...

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Detalles Bibliográficos
Autores principales: Prados, Jose, Melguizo, Consolación, Marchal, Juan Antonio, Vélez, Celia, Alvarez, Luis, Aránega, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926126/
https://www.ncbi.nlm.nih.gov/pubmed/10470293
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00816.x