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A pilot study of the modulation of sirtuins on arylamine N-acetyltransferase 1 and 2 enzymatic activity

Arylamine N-acetyltransferase (NAT; E.C. 2.3.1.5) enzymes are responsible for the biotransformation of several arylamine and hydrazine drugs by acetylation. In this process, the acetyl group transferred to the acceptor substrate produces NAT deacetylation and, in consequence, it is susceptible of de...

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Detalles Bibliográficos
Autores principales: Turiján-Espinoza, Eneida, Salazar-González, Rául Alejandro, Uresti-Rivera, Edith Elena, Hernández-Hernández, Gloria Estela, Ortega-Juárez, Montserrat, Milán, Rosa, Portales-Pérez, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926248/
https://www.ncbi.nlm.nih.gov/pubmed/29719779
http://dx.doi.org/10.1016/j.apsb.2017.11.008