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A pilot study of the modulation of sirtuins on arylamine N-acetyltransferase 1 and 2 enzymatic activity
Arylamine N-acetyltransferase (NAT; E.C. 2.3.1.5) enzymes are responsible for the biotransformation of several arylamine and hydrazine drugs by acetylation. In this process, the acetyl group transferred to the acceptor substrate produces NAT deacetylation and, in consequence, it is susceptible of de...
Autores principales: | Turiján-Espinoza, Eneida, Salazar-González, Rául Alejandro, Uresti-Rivera, Edith Elena, Hernández-Hernández, Gloria Estela, Ortega-Juárez, Montserrat, Milán, Rosa, Portales-Pérez, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926248/ https://www.ncbi.nlm.nih.gov/pubmed/29719779 http://dx.doi.org/10.1016/j.apsb.2017.11.008 |
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