Allelic Loss of 14q and 22q, NF2 Mutation, and Genetic Instability Occur Independently of c‐kit Mutation in Gastrointestinal Stromal Tumor

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Since c‐kit mutation occurs only in one‐third of GIST, there might be other molecular mechanisms. Loss of heterozygosity (LOH), microsatellite instability (MSI) and NF2 gene mutation were invest...

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Detalles Bibliográficos
Autores principales: Fukasawa, Tomoki, Chong, Ja‐Mun, Sakurai, Shinji, Koshiishi, Naoki, Ikeno, Rie, Tanaka, Akira, Matsumoto, Yoshiro, Hayashi, Yukiko, Koike, Morio, Fukayama, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926300/
https://www.ncbi.nlm.nih.gov/pubmed/11123422
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00910.x

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