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Enhanced Cell Killing by Overexpression of Dominant‐negative Phosphatidylinositol 3‐Kinase Subunit, Δp85, Following Genotoxic Stresses

Phosphatidylinositol 3‐kinase (PI3‐K) is a heterodimer of a regulatory subunit, p85, and a catalytic subunit, p110. A number of previous reports showed that PI3‐K functions in diverse cellular phenomena such as cell proliferation, glucose catabolism, cell adhesion, and vesicle transport. It is also...

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Detalles Bibliográficos
Autores principales: Tachiiri, Seiji, Sasai, Keisuke, Oya, Natsuo, Hiraoka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926311/
https://www.ncbi.nlm.nih.gov/pubmed/11123431
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00919.x