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Mycobacteria-derived biomarkers for tuberculosis diagnosis
Tuberculosis (TB) remains an escalating problem worldwide. The current diagnostic methods do not always guarantee reliable diagnosis. TB treatment is a time-consuming process that requires the use of several chemotherapeutics, to which mycobacteria are becoming increasingly resistant. This article f...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926340/ https://www.ncbi.nlm.nih.gov/pubmed/29664027 http://dx.doi.org/10.4103/ijmr.IJMR_1441_16 |
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author | Druszczynska, Magdalena Wawrocki, Sebastian Szewczyk, Rafal Rudnicka, Wieslawa |
author_facet | Druszczynska, Magdalena Wawrocki, Sebastian Szewczyk, Rafal Rudnicka, Wieslawa |
author_sort | Druszczynska, Magdalena |
collection | PubMed |
description | Tuberculosis (TB) remains an escalating problem worldwide. The current diagnostic methods do not always guarantee reliable diagnosis. TB treatment is a time-consuming process that requires the use of several chemotherapeutics, to which mycobacteria are becoming increasingly resistant. This article focuses on the potential utility of biomarkers of mycobacterial origin with potential implications for TB diagnosis. Properly standardized indicators could become new diagnostic tools, improving and streamlining the identification of Mycobacterium tuberculosis infection and the implementation of appropriate therapy. These markers can also potentially provide a quick confirmation of effectiveness of new anti-mycobacterial drugs and TB vaccines, leading to a possible application in practice. |
format | Online Article Text |
id | pubmed-5926340 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59263402018-05-08 Mycobacteria-derived biomarkers for tuberculosis diagnosis Druszczynska, Magdalena Wawrocki, Sebastian Szewczyk, Rafal Rudnicka, Wieslawa Indian J Med Res Review Article Tuberculosis (TB) remains an escalating problem worldwide. The current diagnostic methods do not always guarantee reliable diagnosis. TB treatment is a time-consuming process that requires the use of several chemotherapeutics, to which mycobacteria are becoming increasingly resistant. This article focuses on the potential utility of biomarkers of mycobacterial origin with potential implications for TB diagnosis. Properly standardized indicators could become new diagnostic tools, improving and streamlining the identification of Mycobacterium tuberculosis infection and the implementation of appropriate therapy. These markers can also potentially provide a quick confirmation of effectiveness of new anti-mycobacterial drugs and TB vaccines, leading to a possible application in practice. Medknow Publications & Media Pvt Ltd 2017-12 /pmc/articles/PMC5926340/ /pubmed/29664027 http://dx.doi.org/10.4103/ijmr.IJMR_1441_16 Text en Copyright: © 2017 Indian Journal of Medical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Druszczynska, Magdalena Wawrocki, Sebastian Szewczyk, Rafal Rudnicka, Wieslawa Mycobacteria-derived biomarkers for tuberculosis diagnosis |
title | Mycobacteria-derived biomarkers for tuberculosis diagnosis |
title_full | Mycobacteria-derived biomarkers for tuberculosis diagnosis |
title_fullStr | Mycobacteria-derived biomarkers for tuberculosis diagnosis |
title_full_unstemmed | Mycobacteria-derived biomarkers for tuberculosis diagnosis |
title_short | Mycobacteria-derived biomarkers for tuberculosis diagnosis |
title_sort | mycobacteria-derived biomarkers for tuberculosis diagnosis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926340/ https://www.ncbi.nlm.nih.gov/pubmed/29664027 http://dx.doi.org/10.4103/ijmr.IJMR_1441_16 |
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