Selective Inhibition of Hepatoma Cells Using Diphtheria Toxin A under the Control of the Promoter/Enhancer Region of the Human α‐Fetoprotein Gene

We constructed a plasmid containing human α‐fetoprotein (AFP) promoter/enhancer to direct the cell type‐specific expression of diphtheria toxin fragment A (DTA), designated as pAF‐DTA, to AFP‐producing hepatocellular carcinoma cells. The transfection was carried out with cationic liposomes (DMRIE‐C)...

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Detalles Bibliográficos
Autores principales: Kunitomi, Michito, Takayama, Eiji, Suzuki, Satoshi, Yasuda, Tatsuji, Tsutsui, Ken, Nagaike, Kazuhiro, Hiroi, Sadayuki, Tadakuma, Takushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926372/
https://www.ncbi.nlm.nih.gov/pubmed/10760695
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00951.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926372/
https://www.ncbi.nlm.nih.gov/pubmed/10760695
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00951.x

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