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Different Mutation Frequencies and Spectra among Organs by N‐Methyl‐N‐nitrosourea in rpsL (strA) Transgenic Mice

The frequencies and spectra of N‐methyl‐N‐nitrosourea (MNU)‐induced in vivo somatic mutations were determined in rpsL (strA) transgenic mice. The wild‐type rpsL gene, which exhibits a streptomycin‐sensitive (Sm(s)) phenotype, was used as the rescue marker gene. Studies of mutation spectra among diff...

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Detalles Bibliográficos
Autores principales:	Shioyama, Yoshiyuki, Gondo, Yoichi, Nakao, Kazuki, Katsuki, Motoya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2000
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926380/ https://www.ncbi.nlm.nih.gov/pubmed/10835492 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00971.x

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