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Avidin Chase Can Reduce Myelotoxicity Associated with Radioimmunotherapy of Experimental Liver Micrometastases in Mice

Myelotoxicity is the main factor which decides the maximum tolerated dose (MTD) in radioimmunotherapy (RIT). Since bone marrow is mostly irradiated from blood radioactivity, enhancing the clearance of unbound circulating radiolabeled antibody is important to reduce myelotoxicity and to increase the...

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Detalles Bibliográficos
Autores principales: Sato, Noriko, Saga, Tsuneo, Sakahara, Harumi, Nakamoto, Yuji, Zhao, Songji, Kuroki, Masahide, Iida, Yasuhiko, Endo, Keigo, Konishi, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926392/
https://www.ncbi.nlm.nih.gov/pubmed/10874215
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00991.x