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Avidin Chase Can Reduce Myelotoxicity Associated with Radioimmunotherapy of Experimental Liver Micrometastases in Mice
Myelotoxicity is the main factor which decides the maximum tolerated dose (MTD) in radioimmunotherapy (RIT). Since bone marrow is mostly irradiated from blood radioactivity, enhancing the clearance of unbound circulating radiolabeled antibody is important to reduce myelotoxicity and to increase the...
Autores principales: | Sato, Noriko, Saga, Tsuneo, Sakahara, Harumi, Nakamoto, Yuji, Zhao, Songji, Kuroki, Masahide, Iida, Yasuhiko, Endo, Keigo, Konishi, Junji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926392/ https://www.ncbi.nlm.nih.gov/pubmed/10874215 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00991.x |
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