TZT‐1027, an Antimicrotubule Agent, Attacks Tumor Vasculature and Induces Tumor Cell Death

TZT‐1027, a dolastatin 10 derivative, is an antimicrotubule agent with potent antitumor activity both in vitro and in vivo. In this study, we performed biochemical and histopathological examinations, and evaluated TZT‐1027‐induced tumoral vascular collapse and tumor cell death in an advanced tumor m...

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Detalles Bibliográficos
Autores principales: Otani, Masashi, Natsume, Tsugitaka, Watanabe, Jun‐ichi, Kobayashi, Motohiro, Murakoshi, Masanori, Mikami, Takashi, Nakayama, Takaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926421/
https://www.ncbi.nlm.nih.gov/pubmed/10965026
http://dx.doi.org/10.1111/j.1349-7006.2000.tb01022.x

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