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Absence of Germline CHK2 Mutations in Familial Gastric Cancer

Recently, the CHK2 gene was identified as being a candidate gene responsible for Li‐Fraumeni syndrome (LFS). Gastric cancer is often clustered in families with LFS, so it is possible that germline CHK2 mutation is also present in familial gastric cancer (FGC). We therefore defined the genomic struct...

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Detalles Bibliográficos
Autores principales: Kimura, Kenji, Shinmura, Kazuya, Yoshimura, Kimio, Shimizu, Kimihiro, Katai, Hitoshi, Beppu, Yasuo, Moriya, Hideshige, Yokota, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926446/
https://www.ncbi.nlm.nih.gov/pubmed/11011113
http://dx.doi.org/10.1111/j.1349-7006.2000.tb01028.x

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