Screening of BRCA1 Mutation Using Immunohistochemical Staining with C‐Terminal and N‐Terminal Antibodies in Familial Ovarian Cancers

We examined the subcellular localization of BRCA1 proteins using immunohistochemical staining with C‐terminal (GLK‐2 antibody) and N‐terminal (Ab‐2 antibody) monoclonal antibodies in 44 familial ovarian cancers. Among these, 24 cases were associated with 13 independent germ‐line mutations of BRCA1,...

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Detalles Bibliográficos
Autores principales: Kashima, Katsunori, Oite, Takashi, Aoki, Yoichi, Takakuwa, Koichi, Aida, Hiroshi, Nagata, Hiroshi, Sekine, Masayuki, Wu, Hong Jun, Hirai, Yasuo, Wada, Yuichi, Yamamoto, Kaichiro, Hasegawa, Kazuo, Sonoda, Takahiko, Maruo, Takeshi, Nagata, Ichiro, Ohno, Masayuki, Suzuki, Mitsuaki, Kobayashi, Iwao, Kuzuya, Kazuo, Takahashi, Takeshi, Torii, Yuichi, Tanaka, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926460/
https://www.ncbi.nlm.nih.gov/pubmed/10804288
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00959.x

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