Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Jørgensen, Astrid-Helene Ravn, Yao, Yiqiu, Thomsen, Simon Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926496/
https://www.ncbi.nlm.nih.gov/pubmed/29850284
http://dx.doi.org/10.1155/2018/8685136
_version_ 1783318918434127872
author Jørgensen, Astrid-Helene Ravn
Yao, Yiqiu
Thomsen, Simon Francis
author_facet Jørgensen, Astrid-Helene Ravn
Yao, Yiqiu
Thomsen, Simon Francis
author_sort Jørgensen, Astrid-Helene Ravn
collection PubMed
description Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A).
format Online
Article
Text
id pubmed-5926496
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-59264962018-05-30 Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa Jørgensen, Astrid-Helene Ravn Yao, Yiqiu Thomsen, Simon Francis Case Rep Dermatol Med Case Report Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A). Hindawi 2018-04-16 /pmc/articles/PMC5926496/ /pubmed/29850284 http://dx.doi.org/10.1155/2018/8685136 Text en Copyright © 2018 Astrid-Helene Ravn Jørgensen et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jørgensen, Astrid-Helene Ravn
Yao, Yiqiu
Thomsen, Simon Francis
Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_full Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_fullStr Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_full_unstemmed Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_short Therapeutic Response to Secukinumab in a 36-Year-Old Woman with Hidradenitis Suppurativa
title_sort therapeutic response to secukinumab in a 36-year-old woman with hidradenitis suppurativa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926496/
https://www.ncbi.nlm.nih.gov/pubmed/29850284
http://dx.doi.org/10.1155/2018/8685136
work_keys_str_mv AT jørgensenastridheleneravn therapeuticresponsetosecukinumabina36yearoldwomanwithhidradenitissuppurativa
AT yaoyiqiu therapeuticresponsetosecukinumabina36yearoldwomanwithhidradenitissuppurativa
AT thomsensimonfrancis therapeuticresponsetosecukinumabina36yearoldwomanwithhidradenitissuppurativa

Ejemplares similares