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Low expression of c-Myc protein predicts poor outcomes in patients with hepatocellular carcinoma after resection

BACKGROUND: Embryonic Liver Fodrin (ELF) is an adaptor protein of transforming growth factor (TGF-β) signaling cascade. Disruption of ELF results in mislocalization of Smad3 and Smad4, leading to compromised TGF-β signaling. c-Myc is an important oncogenic transcription factor, and the disruption of...

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Detalles Bibliográficos
Autores principales: Ji, Fei, Zhang, Zhi-heng, Zhang, Yi, Shen, Shun-Li, Cao, Qing-Hua, Zhang, Long-Juan, Li, Shao-Qiang, Peng, Bao-Gang, Liang, Li-Jian, Hua, Yun-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926532/
https://www.ncbi.nlm.nih.gov/pubmed/29690860
http://dx.doi.org/10.1186/s12885-018-4379-5