OCEAN-C: mapping hubs of open chromatin interactions across the genome reveals gene regulatory networks

We develop a method called open chromatin enrichment and network Hi-C (OCEAN-C) for antibody-independent mapping of global open chromatin interactions. By integrating FAIRE-seq and Hi-C, OCEAN-C detects open chromatin interactions enriched by active cis-regulatory elements. We identify more than 10,...

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Detalles Bibliográficos
Autores principales: Li, Tingting, Jia, Lumeng, Cao, Yong, Chen, Qing, Li, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926533/
https://www.ncbi.nlm.nih.gov/pubmed/29690904
http://dx.doi.org/10.1186/s13059-018-1430-4

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