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Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults
BACKGROUND: T-cell responses against highly conserved influenza antigens have been previously associated with protection. However, these immune responses are poorly maintained following recovery from influenza infection and are not boosted by inactivated influenza vaccines. We have previously demons...
Autores principales: | Coughlan, L., Sridhar, S., Payne, R., Edmans, M., Milicic, A., Venkatraman, N., Lugonja, B., Clifton, L., Qi, C., Folegatti, P.M., Lawrie, A.M., Roberts, R., de Graaf, H., Sukhtankar, P., Faust, S.N., Lewis, D.J.M., Lambe, T., Hill, AVS, Gilbert, S.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926543/ https://www.ncbi.nlm.nih.gov/pubmed/29519670 http://dx.doi.org/10.1016/j.ebiom.2018.02.011 |
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