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Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults

BACKGROUND: T-cell responses against highly conserved influenza antigens have been previously associated with protection. However, these immune responses are poorly maintained following recovery from influenza infection and are not boosted by inactivated influenza vaccines. We have previously demons...

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Detalles Bibliográficos
Autores principales: Coughlan, L., Sridhar, S., Payne, R., Edmans, M., Milicic, A., Venkatraman, N., Lugonja, B., Clifton, L., Qi, C., Folegatti, P.M., Lawrie, A.M., Roberts, R., de Graaf, H., Sukhtankar, P., Faust, S.N., Lewis, D.J.M., Lambe, T., Hill, AVS, Gilbert, S.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926543/
https://www.ncbi.nlm.nih.gov/pubmed/29519670
http://dx.doi.org/10.1016/j.ebiom.2018.02.011

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