Oxidative DNA Damage Induced by an N‐Hydroxy Metabolite of Carcinogenic 4‐Dimethylaminoazobenzene

Formation of adducts has been considered to be a major causal factor of DNA damage by carcinogenic aminoazo dyes. We investigated whether a metabolite of hepatocarcinogenic 4‐dimethylaminoazobenzene (DAB) can cause oxidative DNA damage or not, using (32)P‐5′‐end‐labeled DNA fragments. The DAB metabo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohnishi, Shiho, Murata, Mariko, Degawa, Masakuni, Kawanishi, Shosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926586/
https://www.ncbi.nlm.nih.gov/pubmed/11173540
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01043.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926586/
https://www.ncbi.nlm.nih.gov/pubmed/11173540
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01043.x

Ejemplares similares