Cargando…

Hypoxia Reduces Hormone Responsiveness of Human Breast Cancer Cells

Resistance to hormonal therapy frequently occurs following successful treatment in breast cancer. The mechanism responsible for this acquired resistance is still unknown. It has been suggested that a hypoxic tumor microenvironment promotes malignant progression of cancer, i.e., hypoxia may promote e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurebayashi, Junichi, Otsuki, Takemi, Moriya, Takuya, Sonoo, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926610/ https://www.ncbi.nlm.nih.gov/pubmed/11676860 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01064.x

Ejemplares similares

A Radicicol Derivative, KF58333, Inhibits Expression of Hypoxia‐inducible Factor‐1α and Vascular Endothelial Growth Factor, Angiogenesis and Growth of Human Breast Cancer Xenografts
por: Kurebayashi, Junichi, et al.
Publicado: (2001)

Expression of Vascular Endothelial Growth Factor (VEGF) Family Members in Breast Cancer
por: Kurebayashi, Junichi, et al.
Publicado: (1999)

Preferential antitumor effect of the Src inhibitor dasatinib associated with a decreased proportion of aldehyde dehydrogenase 1-positive cells in breast cancer cells of the basal B subtype
por: Kurebayashi, Junichi, et al.
Publicado: (2010)

Medroxyprogesterone acetate inhibits interleukin 6 secretion from KPL-4 human breast cancer cells both in vitro and in vivo: a possible mechanism of the anticachectic effect
por: Kurebayashi, J, et al.
Publicado: (1999)

Parathyroid hormone-related protein secretion is inhibited by oestradiol and stimulated by antioestrogens in KPL-3C human breast cancer cells.
por: Kurebayashi, J., et al.
Publicado: (1997)

A new human breast cancer cell line, KPL-3C, secretes parathyroid hormone-related protein and produces tumours associated with microcalcifications in nude mice.
por: Kurebayashi, J., et al.
Publicado: (1996)

Additive antitumour effect of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa, ZD1839) and the antioestrogen fulvestrant (Faslodex, ICI 182,780) in breast cancer cells
por: Okubo, S, et al.
Publicado: (2004)

A new human breast cancer cell line, KPL-1 secretes tumour-associated antigens and grows rapidly in female athymic nude mice.
por: Kurebayashi, J., et al.
Publicado: (1995)

Anti‐cancer stem cell activity of a hedgehog inhibitor GANT61 in estrogen receptor‐positive breast cancer cells
por: Kurebayashi, Junichi, et al.
Publicado: (2017)

Targeted next-generation sequencing assays using triplet samples of normal breast tissue, primary breast cancer, and recurrent/metastatic lesions
por: Akahane, Toshiaki, et al.
Publicado: (2020)

CD1d- and PJA2-related immune microenvironment differs between invasive breast carcinomas with and without a micropapillary feature
por: Kanomata, Naoki, et al.
Publicado: (2019)

Anti-HER2 antibody enhances the growth inhibitory effect of anti-oestrogen on breast cancer cells expressing both oestrogen receptors and HER2
por: Kunisue, H, et al.
Publicado: (2000)

Preparation of a novel antiserum to aromatase with high affinity and specificity: Its clinicopathological significance on breast cancer tissue
por: Kanomata, Naoki, et al.
Publicado: (2017)

Correction: Preparation of a novel antiserum to aromatase with high affinity and specificity: Its clinicopathological significance on breast cancer tissue
por: Kanomata, Naoki, et al.
Publicado: (2017)

Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6
por: Kurebayashi, J, et al.
Publicado: (1999)

Analysis of Clinical Outcome of Patients with Poorly Differentiated Thyroid Carcinoma
por: Tanaka, Katsuhiro, et al.
Publicado: (2011)

Efficacy and safety of leuprorelin acetate 6-month depot, TAP-144-SR (6M), in combination with tamoxifen in postoperative, premenopausal patients with hormone receptor-positive breast cancer: a phase III, randomized, open-label, parallel-group comparative study
por: Kurebayashi, Junichi, et al.
Publicado: (2016)

Resistance to cyclin-dependent kinase (CDK) 4/6 inhibitors confers cross-resistance to other CDK inhibitors but not to chemotherapeutic agents in breast cancer cells
por: Ogata, Ryohei, et al.
Publicado: (2020)

A follow-up study of a randomized controlled study evaluating safety and efficacy of leuprorelin acetate every-3-month depot for 2 versus 3 or more years with tamoxifen for 5 years as adjuvant treatment in premenopausal patients with endocrine-responsive breast cancer
por: Kurebayashi, Junichi, et al.
Publicado: (2021)

Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8(+) T Cell Line following Long-Term Exposure to Asbestos Fibers
por: Kumagai-Takei, Naoko, et al.
Publicado: (2018)

The Effects of Asbestos Fibers on Human T Cells
por: Kumagai-Takei, Naoko, et al.
Publicado: (2020)

Mild Hypobaric Hypoxia Enhances Post-exercise Vascular Responses in Young Male Runners
por: Saito, Yoko, et al.
Publicado: (2019)

Differential response of luminal and basal breast cancer cells to acute and chronic hypoxia
por: Liu, Qiuyu, et al.
Publicado: (2023)

Hypoxia and oxidative stress in breast cancer: Hypoxia and tumourigenesis
por: Knowles, Helen J, et al.
Publicado: (2001)

Correlations between physical activity and neurocognitive domain functions in patients with schizophrenia: a cross-sectional study
por: Kurebayashi, Yusuke, et al.
Publicado: (2017)

Immunological Effects of Environmental Factors: Focus on the Fibrous and Particulated Materials
por: Otsuki, Takemi, et al.
Publicado: (2014)

BlyS is up-regulated by hypoxia and promotes migration of human breast cancer cells
por: Zhu, Jing, et al.
Publicado: (2012)

Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells
por: Han, Jian, et al.
Publicado: (2017)

Hypoxia induced responses are reflected in the stromal proteome of breast cancer
por: Kjølle, Silje, et al.
Publicado: (2023)

A randomized controlled study evaluating safety and efficacy of leuprorelin acetate every-3-months depot for 2 versus 3 or more years with tamoxifen for 5 years as adjuvant treatment in premenopausal patients with endocrine-responsive breast cancer
por: Shiba, Eiichi, et al.
Publicado: (2015)

Stress-related hormone reduces autophagy through the regulation of phosphatidylethanolamine in breast cancer cells
por: Zhu, Zhen, et al.
Publicado: (2021)

Recent declines in breast cancer incidence: mounting evidence that reduced use of menopausal hormones is largely responsible
por: Banks, Emily, et al.
Publicado: (2010)

Comparison of quality of life between 2-year and 3-or-more-year administration of leuprorelin acetate every-3-months depot in combination with tamoxifen as adjuvant endocrine treatment in premenopausal patients with endocrine-responsive breast cancer: a randomized controlled trial
por: Ohashi, Yasuo, et al.
Publicado: (2017)

Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells
por: Kitagawa, Koh, et al.
Publicado: (2020)

Altered radiation responses of breast cancer cells resistant to hormonal therapy
por: Luzhna, Lidiya, et al.
Publicado: (2014)

Asbestos Induces Reduction of Tumor Immunity
por: Kumagai-Takei, Naoko, et al.
Publicado: (2011)

Ingredients such as trehalose and hesperidin taken as supplements or foods reverse alterations in human T cells, reducing asbestos exposure-induced antitumor immunity
por: Yamamoto, Shoko, et al.
Publicado: (2021)

Hypoxia and oxidative stress in breast cancer: Hypoxia signalling pathways
por: Pugh, Christopher W, et al.
Publicado: (2001)

Inflammatory Alteration of Human T Cells Exposed Continuously to Asbestos
por: Kumagai-Takei, Naoko, et al.
Publicado: (2018)

Hypoxia-inducible factor 1 mediates intermittent hypoxia-induced migration of human breast cancer MDA-MB-231 cells
por: Liu, Litao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pmu3e3ferf90os6f6eb88gu5up