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Antitumor Effect of the Idiotypic Cascade Induced by an Antibody Encapsulated in Poly(d, l‐lactide‐co‐glycolide) Microspheres
A major difficulty encountered during development of antibody vaccines is their weak immunogenicity. In this study, a monoclonal antibody CS20.5 to human breast cancer antigen CA15.3 was coencapsulated in poly(d, l‐lactide‐co‐glycolide) microspheres with monophosphoryl lipid A. The antitumor effect...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926615/ https://www.ncbi.nlm.nih.gov/pubmed/11676862 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01066.x |