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Antitumor Effect of the Idiotypic Cascade Induced by an Antibody Encapsulated in Poly(d, l‐lactide‐co‐glycolide) Microspheres

A major difficulty encountered during development of antibody vaccines is their weak immunogenicity. In this study, a monoclonal antibody CS20.5 to human breast cancer antigen CA15.3 was coencapsulated in poly(d, l‐lactide‐co‐glycolide) microspheres with monophosphoryl lipid A. The antitumor effect...

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Detalles Bibliográficos
Autores principales: Ma, Jie, Luo, Dong, Qi, Weimin, Cao, Liren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926615/
https://www.ncbi.nlm.nih.gov/pubmed/11676862
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01066.x

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