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p53 and H‐ras Mutations and Microsatellite Instability in Renal Pelvic Carcinomas of NON/Shi Mice Treated with N‐Butyl‐N‐(4‐hydroxybutyl)‐nitrosamine: Different Genetic Alteration from Urinary Bladder Carcinoma

We previously reported p53 mutations to be frequent (greater than 70%), whereas both H‐ras mutations and microsatellite instability (MSI) were infrequent (about 10%), in urinary bladder carcinomas (UBCs) and their metastatic foci in the N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN)‐induced mouse uroth...

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Detalles Bibliográficos
Autores principales: Gen, Hiroyuki, Yamamoto, Shinji, Morimura, Keiichirou, Min, Wei, Mitsuhashi, Makoto, Murai, Takashi, Mori, Satoru, Hosono, Motoko, Oohara, Tadao, Makino, Susumu, Wanibuchi, Hideki, Fukushima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926685/
https://www.ncbi.nlm.nih.gov/pubmed/11749692
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02150.x