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Pharmacodynamic Modeling of the Entire Time Course of Leukopenia after a 3‐Hour Infusion of Paclitaxel

The entire time course of leukopenia after anticancer treatment is clinically more relevant than a singly measured nadir count. In order to identify factors associated with neutropenic fever, a mechanistic pharmacodynamic model with two compartments corresponding to leukocytes in bone marrow and per...

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Detalles Bibliográficos
Autores principales: Minami, Hironobu, Sasaki, Yasutsuna, Watanabe, Torn, Ogawa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926694/
https://www.ncbi.nlm.nih.gov/pubmed/11223553
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01086.x