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Mutations of p53 in Morphologically Non‐neoplastic Mucosa of Long‐standing Ulcerative Colitis

Two cases of ulcerative colitis (UC)‐associated carcinoma or dysplasia and morphologically non‐neoplastic mucosa with p53 protein overexpression (MNNM‐p53OE) were selected. DNA was extracted from the paraffin blocks of these lesions and exons 5‐8 of the p53 gene were analyzed by PCR and direct seque...

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Detalles Bibliográficos
Autores principales: Takaku, Hideya, Ajioka, Yoichi, Watanabe, Hidenobu, Hashidate, Hideki, Yamada, Satoshi, Yokoyama, Junji, Kazama, Shinsuke, Suda, Takeyasu, Hatakeyama, Katsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926702/
https://www.ncbi.nlm.nih.gov/pubmed/11223540
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01073.x