Cargando…

Aberrant Expression of pRb, p16, p14ARF, MDM2, p21 and p53 in Squamous Cell Carcinomas of Lung

Expression of cell cycle regulatory proteins in both the RB and p53 pathways was investigated in 50 cases of squamaous cell carcinoma (SCC) of the lung using immunohistochemical techniques.Abnormality of pRb and p16 expression was seen at the frequencies of 16% and 78%, respectively, and appeared to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xue, Qi, Sano, Takaaki, Kashiwabara, Kenji, Oyama, Tetsunari, Nakajima, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926708/ https://www.ncbi.nlm.nih.gov/pubmed/11267938 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01093.x

Ejemplares similares

The effects of fucodian on senescence are controlled by the p16(INK4a)-pRb and p14(Arf)-p53 pathways in hepatocellular carcinoma and hepatic cell lines
por: MIN, EUN-YOUNG, et al.
Publicado: (2014)

Antitumor mechanisms when pRb and p53 are genetically inactivated
por: Zhu, Liang, et al.
Publicado: (2014)

Treating cancer when pRb and p53 cannot be reactivated
por: Zhu, Liang
Publicado: (2015)

p16, pRb, and p53 in Feline Oral Squamous Cell Carcinoma
por: Supsavhad, Wachiraphan, et al.
Publicado: (2016)

Prediction of progression in pTa and pT1 bladder carcinomas with p53, p16 and pRb
por: Hitchings, A W, et al.
Publicado: (2004)

The In Vivo Role of the RP-Mdm2-p53 Pathway in Signaling Oncogenic Stress Induced by pRb Inactivation and Ras Overexpression
por: Pan, Wenqi, et al.
Publicado: (2011)

Pinning Control for the p53-Mdm2 Network Dynamics Regulated by p14ARF
por: Suarez, Oscar J., et al.
Publicado: (2020)

The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence
por: Haferkamp, Sebastian, et al.
Publicado: (2009)

Expression of pRb, p53, p16 and Cyclin D1 and Their Clinical Implications in Urothelial Carcinoma
por: Lee, Kyungji, et al.
Publicado: (2010)

Molecular Signature of HPV-Induced Carcinogenesis: pRb, p53 and Gene Expression Profiling
por: Buitrago-Pérez, Águeda, et al.
Publicado: (2009)

Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21
por: Kazem, Siamaque, et al.
Publicado: (2014)

Jun dimerization protein 2 controls hypoxia‐induced replicative senescence via both the p16(Ink4a)‐pRb and Arf‐p53 pathways
por: Nakade, Koji, et al.
Publicado: (2017)

Relevance of pRB Loss in Human Malignancies
por: Mandigo, Amy C., et al.
Publicado: (2022)

Deficiency of G1 regulators P53, P21(Cip1 )and/or pRb decreases hepatocyte sensitivity to TGFβ cell cycle arrest
por: Sheahan, Sharon, et al.
Publicado: (2007)

Overexpression of CCDC69 activates p14(ARF)/MDM2/p53 pathway and confers cisplatin sensitivity
por: Cui, Long, et al.
Publicado: (2019)

Roles of pRB in the Regulation of Nucleosome and Chromatin Structures
por: Uchida, Chiharu
Publicado: (2016)

p130 And pRb in the Maintenance of Transient Quiescence of Mesenchymal Stem Cells
por: Popov, Boris, et al.
Publicado: (2020)

Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines
por: Huun, Johanna, et al.
Publicado: (2017)

Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation
por: Maylina, Leni, et al.
Publicado: (2022)

An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence
por: Rovillain, Emilie, et al.
Publicado: (2011)

Prognostic Significance of Immunohistochemical Expression of p53 and Retinoblastoma Gene Protein (pRB) in Curatively Resected Gastric Cancer
por: Song, Hong Suk, et al.
Publicado: (2005)

Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN‐amplified retinoblastoma
por: Ewens, Kathryn G., et al.
Publicado: (2017)

Loss of Heterozygosities in Five Tumor Suppressor Genes (FHIT Gene, p16, pRb, E-Cadherin and p53) in Thyroid Tumors
por: Kim, Jin Hwan, et al.
Publicado: (2014)

Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma
por: Plath, Michaela, et al.
Publicado: (2018)

pRb or its cousins: Who controls the family business?
por: Itahana, Koji, et al.
Publicado: (2012)

LRP6 targeting suppresses gastric tumorigenesis via P14(ARF)–Mdm2–P53-dependent cellular senescence
por: Wang, Haibin, et al.
Publicado: (2017)

Differential expression of cyclin D1, Ki-67, pRb, and p53 in psoriatic skin lesions and normal skin
por: Kim, Sung Ae, et al.
Publicado: (2018)

Concomitant inactivation of the p53‐ and pRB‐ functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo
por: Knappskog, Stian, et al.
Publicado: (2015)

Effects of high-risk human papillomavirus infection on P53, pRb, and survivin in lung adenocarcinoma—a retrospective study
por: Sun, Wenwen, et al.
Publicado: (2023)

The Senescence Markers p16INK4A, p14ARF/p19ARF, and p21 in Organ Development and Homeostasis
por: Wagner, Kay-Dietrich, et al.
Publicado: (2022)

Cell cycle regulators p27 and pRb in lymphomas – correlation with histology and proliferative activity
por: Kiviniemi, M, et al.
Publicado: (2000)

Human papillomavirus infection and immunohistochemical expression of cell cycle proteins pRb, p53, and p16(INK4a) in sinonasal diseases
por: Yamashita, Yukashi, et al.
Publicado: (2015)

Cell cycle regulation: p53-p21-RB signaling
por: Engeland, Kurt
Publicado: (2022)

FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest
por: Laplantine, Emmanuel, et al.
Publicado: (2002)

Correction: NLRP6 targeting suppresses gastric tumorigenesis via P14(ARF)–Mdm2–P53-dependent cellular senescence
por: Wang, Haibin, et al.
Publicado: (2018)

pRb controls Estrogen Receptor alpha protein stability and activity
por: Caligiuri, Isabella, et al.
Publicado: (2013)

Cyclin D1 expression in transitional cell carcinoma of the bladder: correlation with p53, waf1, pRb and Ki67
por: Tut, V M, et al.
Publicado: (2001)

RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells
por: Carper, Miranda B., et al.
Publicado: (2014)

Expression of Cell-Cycle Regulatory Proteins pRb, Cyclin D1, and p53 Is Not Associated with Recurrence Rates of Equine Sarcoids
por: Tura, Giorgia, et al.
Publicado: (2022)

pRB-Depleted Pluripotent Stem Cell Retinal Organoids Recapitulate Cell State Transitions of Retinoblastoma Development and Suggest an Important Role for pRB in Retinal Cell Differentiation
por: Rozanska, Agata, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hjtkt6884onb5hn0jjvthjmkqa