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Antitumor Activity and Pharmacokinetics of TAS‐106, l‐(3‐C‐Ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosine
We examined the effects of dosage schedule on antitumor activity in vitro and in vivo to determine the optimal administration schedule for a new nucleoside antimetabolite l‐(3‐C‐ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosine (ECyd, TAS‐106). The cytotoxicity of TAS‐106 in vitro against human tumors was ev...
Autores principales: | Shimamoto, Yuji, Fujioka, Akio, Kazuno, Hiromi, Murakami, Yuko, Ohshimo, Hideyuki, Kato, Toshiyuki, Matsuda, Akira, Sasaki, Takuma, Fukushima, Masakazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926715/ https://www.ncbi.nlm.nih.gov/pubmed/11267946 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01101.x |
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