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Enhanced Vascular Permeability in Solid Tumor Involving Peroxynitrite and Matrix Metalloproteinases

Peroxynitrite (ONOO ‐), which is generated from nitric oxide (NO) and superoxide anion (O(2)‐) under pathological conditions, plays an important role in pathophysiological processes. Activation of matrix metalloproteinases (MMPs) contributes to tumor angiogenesis and metastasis. NO mediates the enha...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Akaike, Takaaki, Hayashida, Kazuyuki, Okamoto, Tatsuya, Okuyama, Akira, Maeda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926730/
https://www.ncbi.nlm.nih.gov/pubmed/11346467
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01114.x