Suicide Gene Therapy for Chemically Induced Rat Bladder Tumor Entailing Instillation of Adenoviral Vectors

The efficacy of an in vivo gene therapy protocol making use of an adenoviral vector in the treatment of bladder cancer was examined. Bladder tumors were induced in rats by oral administration of BBN (N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine). Histologically, such tumors resemble those seen in human bla...

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Detalles Bibliográficos
Autores principales: Akasaka, Shuji, Suzuki, Satoru, Shimizu, Hiroyuki, Igarashi, Takehito, Akimoto, Masao, Shimada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926741/
https://www.ncbi.nlm.nih.gov/pubmed/11376567
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01131.x

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