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X‐Irradiation Induces Up‐regulation of ATM Gene Expression in Wild‐type Lymphoblastoid Cell Lines, but Not in Their Heterozygous or Homozygous Ataxia‐telangiectasia Counterparts

Ataxia‐telangiectasia (AT) is an autosomal recessive disease. The relevant gene has been cloned and designated ATM. We studied the expression of both ATM mRNA and the ATM protein in unirradi‐ated and X‐irradiated EBV (Epstein‐Barr virus)‐transformed lymphoblastoid cell lines (LCLs) derived from dono...

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Detalles Bibliográficos
Autores principales: Hirai, Yuko, Hayashi, Tomonori, Kubo, Yoshiko, Hoki, Yuko, Arita, Izumi, Tatsumi, Kouichi, Seyama, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926759/
https://www.ncbi.nlm.nih.gov/pubmed/11429062
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01152.x

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