Cargando…
Deletion Mutants of Human Deoxycytidine Kinase mRNA in Cells Resistant to Antitumor Cytosine Nucleosides
We studied mutational events in deoxycytidine (dCyd) kinase mRNA expression, focusing on aberrant dCyd kinase mRNA, which has been frequently observed in established cell lines resistant to antitumor dCyd nucleoside analogues such as 1‐β‐D‐arabinofuranosyl cytosine (Ara‐C), gemcita‐bine (dFdC) and 2...
Autores principales: | Obata, Tohru, Endo, Yoshio, Tanaka, Motohiro, Uchida, Hiroyuki, Matsuda, Akira, Sasaki, Takuma |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926779/ https://www.ncbi.nlm.nih.gov/pubmed/11473731 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01163.x |
Ejemplares similares
-
Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice
por: Maeda, Naoyoshi, et al.
Publicado: (2020) -
Antitumor Activity and Pharmacokinetics of TAS‐106, l‐(3‐C‐Ethynyl‐β‐D‐ribo‐pentofuranosyl)cytosine
por: Shimamoto, Yuji, et al.
Publicado: (2001) -
Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia.
por: Richel, D. J., et al.
Publicado: (1988) -
A nucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (TAS106), sensitizes cells to radiation by suppressing BRCA2 expression
por: Meike, Shunsuke, et al.
Publicado: (2011) -
Structural basis for activation of the therapeutic l-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase
por: Sabini, Elisabetta, et al.
Publicado: (2007)