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Enhancement of in vivo Antitumor Activity of a Novel Antimitotic 1‐Phenylpropenone Derivative, AM‐132, by Tumor Necrosis Factor‐cc or Interleukin‐6

TK5048 and its derivatives, AM‐132, AM‐138, and AM‐97, are recently developed antimitotic (AM) compounds. These 1‐phenylpropenone derivatives induce cell cycle arrest at the G2/M phase of the cell cycle. TK5048 inhibited tubulin polymerization in human lung cancer PC‐14 cells in a concentration‐depe...

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Detalles Bibliográficos
Autores principales:	Tatsumi, Yasuaki, Arioka, Hitoshi, Ikeda, Shun‐ichi, Fukumoto, Hisao, Miyamoto, Ken‐ichi, Fukuoka, Kazuya, Ohe, Yuichiro, Saijo, Nagahiro, Nishio, Kazuto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926787/ https://www.ncbi.nlm.nih.gov/pubmed/11473728 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01160.x

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