Cargando…

Mitotic Checkpoint Protein hsMAD2 as a Marker Predicting Liver Metastasis of Human Gastric Cancers

hsMAD2, the human homologue of mitotic arrest deficient 2 (MAD2), is a key component of the mitotic checkpoint system. Recently, mutations and decreased expression of mitotic checkpoint genes including hsMAD2 have been reported in cancer cell lines with defective mitotic checkpoint. However, the gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanaka, Kouji, Nishioka, Junji, Kato, Keiko, Nakamura, Akiko, Mouri, Tomomi, Miki, Chikao, Kusunoki, Masato, Nobori, Tsutomu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926839/ https://www.ncbi.nlm.nih.gov/pubmed/11572763 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01186.x

Ejemplares similares

Mutational Inactivation of Mitotic Checkpoint Genes, hsMAD2 and hBUB1, Is Rare in Sporadic Digestive Tract Cancers
por: Imai, Yasuo, et al.
Publicado: (1999)

WT1 Interacts with MAD2 and Regulates Mitotic Checkpoint Function
por: Shandilya, Jayasha, et al.
Publicado: (2014)

Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint
por: Ballister, Edward R., et al.
Publicado: (2014)

The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex
por: Chen, Chu, et al.
Publicado: (2023)

Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model
por: Yu, Hongtao
Publicado: (2006)

Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint
por: Allan, Lindsey A, et al.
Publicado: (2020)

Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly
por: Fischer, Elyse S., et al.
Publicado: (2022)

Deletion of Dinucleotide Repeat (Δ14 Allele) in the Methylthioadenosine Phosphorylase (MTAP) Promoter and the Allelotype of MTAP Promoter in the Japanese Population
por: Kadariya, Yuwaraj, et al.
Publicado: (2002)

Maternal genetic polymorphisms in the major mitotic checkpoint genes MAD1L1 and MAD2L1 associated with the risk of survival in abnormal chromosomal fetuses
por: Chan, Ying, et al.
Publicado: (2023)

Mad2 inhibits the mitotic kinesin MKlp2
por: Lee, Sang Hyun, et al.
Publicado: (2010)

The Maize Homologue of the Cell Cycle Checkpoint Protein MAD2 Reveals Kinetochore Substructure and Contrasting Mitotic and Meiotic Localization Patterns
por: Yu, Hong-Guo, et al.
Publicado: (1999)

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma
por: Chuah, You Heng, et al.
Publicado: (2023)

p31(comet) inactivates the chemically induced Mad2-dependent spindle assembly checkpoint and leads to resistance to anti-mitotic drugs
por: Habu, Toshiyuki, et al.
Publicado: (2013)

MAD2L2 helps mitotic cells take it slow
por: Short, Ben
Publicado: (2013)

Mitotic checkpoints, MUGs and kinetochores
por: Brinkley, Bill R.
Publicado: (2013)

Budding Yeast Bub2 Is Localized at Spindle Pole Bodies and Activates the Mitotic Checkpoint via a Different Pathway from Mad2
por: Fraschini, Roberta, et al.
Publicado: (1999)

Kinetochore localized Mad2 and Cdc20 is itself insufficient for triggering the mitotic checkpoint when Mps1 is low in Drosophila melanogaster neuroblasts
por: Herriott, Ashleigh, et al.
Publicado: (2012)

A Bub1–Mad1 interaction targets the Mad1–Mad2 complex to unattached kinetochores to initiate the spindle checkpoint
por: Moyle, Mark W., et al.
Publicado: (2014)

Caspase activity is not required for the mitotic checkpoint or mitotic slippage in human cells
por: Lee, Kyunghee, et al.
Publicado: (2011)

MAD2γ, a novel MAD2 isoform, reduces mitotic arrest and is associated with resistance in testicular germ cell tumors
por: López-Saavedra, Alejandro, et al.
Publicado: (2016)

Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer
por: Yang, Maojun, et al.
Publicado: (2008)

Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor–mediated metaphase arrest
por: Tunquist, Brian J., et al.
Publicado: (2003)

Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores
por: Heinrich, Stephanie, et al.
Publicado: (2014)

Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis
por: Schweizer, Nina, et al.
Publicado: (2013)

AAV2/8-hSMAD3 gene delivery attenuates aortic atherogenesis, enhances Th2 response without fibrosis, in LDLR-KO mice on high cholesterol diet
por: Zhu, Hongqing, et al.
Publicado: (2014)

Mad3 KEN Boxes Mediate both Cdc20 and Mad3 Turnover, and Are Critical for the Spindle Checkpoint
por: King, Emma M.J., et al.
Publicado: (2007)

OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases
por: Ji, Wenbin, et al.
Publicado: (2016)

Rare case of retroperitoneal mitotically active leiomyoma in a postmenopausal woman
por: Doita, Susumu, et al.
Publicado: (2023)

In-Silico Modeling of the Mitotic Spindle Assembly Checkpoint
por: Ibrahim, Bashar, et al.
Publicado: (2008)

Targeting the Mitotic Checkpoint to Kill Tumor Cells
por: Janssen, Aniek, et al.
Publicado: (2010)

Some assembly required: Redefining the mitotic checkpoint
por: Meadows, John C., et al.
Publicado: (2017)

Analysis of the role of GSK3 in the mitotic checkpoint
por: Rashid, M. S., et al.
Publicado: (2018)

Regulation of mitotic progression by the spindle assembly checkpoint
por: Lischetti, Tiziana, et al.
Publicado: (2015)

Basis of catalytic assembly of the mitotic checkpoint complex
por: Faesen, Alex C., et al.
Publicado: (2017)

Mammalian p55CDC Mediates Association of the Spindle Checkpoint Protein Mad2 with the Cyclosome/Anaphase-promoting Complex, and is Involved in Regulating Anaphase Onset and Late Mitotic Events
por: Kallio, Marko, et al.
Publicado: (1998)

ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint
por: Yuan, Fengjie, et al.
Publicado: (2019)

PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores
por: Montembault, Emilie, et al.
Publicado: (2007)

The Spindle Checkpoint Functions of Mad3 and Mad2 Depend on a Mad3 KEN Box-mediated Interaction with Cdc20-Anaphase-promoting Complex (APC/C)
por: Sczaniecka, Matylda, et al.
Publicado: (2008)

Late-onset peritoneal recurrence of advanced gastric cancer 20 years after primary resection
por: Okugawa, Yoshinaga, et al.
Publicado: (2010)

Evaluation of preoperative C-reactive protein aids in predicting poor survival in patients with curative colorectal cancer with poor lymph node assessment
por: TOIYAMA, YUJI, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_v1ip9mlacc1a7e3utculhponet