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Phosphorylation of Fas‐associated Death Domain Contributes to Enhancement of Etoposide‐induced Apoptosis in Prostate Cancer Cells
Fas‐associated death domain (FADD) plays an important role as an adapter molecule in Fas (CD95/APO‐l)‐mediated apoptosis and contributes to anticancer drug‐induced cytotoxicity. We treated three human prostate cancer cell lines with etoposide, a toposiomerase II inhibitor with activity against vario...
Autores principales: | Shimada, Keiji, Nakamura, Mitsutoshi, Ishida, Eiwa, Kishi, Munehiro, Yonehara, Shin, Konishi, Noboru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926882/ https://www.ncbi.nlm.nih.gov/pubmed/12417047 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01219.x |
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