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l‐β‐D‐Arabinofuranosylcytosine Is Cytotoxic in Quiescent Normal Lymphocytes Undergoing DNA Excision Repair

We have sought to clarify the potential activity of the S‐phase‐specific antileukemic agent 1‐β‐D‐arabinofuranosylcytosine (ara‐C), an inhibitor of DNA synthesis, in quiescent cells that are substantially non‐sensitive to nucleoside analogues. It was hypothesized that the combination of ara‐C with D...

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Detalles Bibliográficos
Autores principales: Yamauchi, Takahiro, Kawai, Yasukazu, Ueda, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926937/
https://www.ncbi.nlm.nih.gov/pubmed/12495473
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01242.x