Cargando…

l‐β‐D‐Arabinofuranosylcytosine Is Cytotoxic in Quiescent Normal Lymphocytes Undergoing DNA Excision Repair

We have sought to clarify the potential activity of the S‐phase‐specific antileukemic agent 1‐β‐D‐arabinofuranosylcytosine (ara‐C), an inhibitor of DNA synthesis, in quiescent cells that are substantially non‐sensitive to nucleoside analogues. It was hypothesized that the combination of ara‐C with D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamauchi, Takahiro, Kawai, Yasukazu, Ueda, Takanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926937/ https://www.ncbi.nlm.nih.gov/pubmed/12495473 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01242.x

Ejemplares similares

Monitoring of Intracellular l‐βD‐Arabinofuranosylcytosine 5′‐Triphosphate in 1‐β‐D‐Arabinofuranosylcytosine Therapy at Low and Conventional Doses
por: Yamauchi, Takahiro, et al.
Publicado: (2001)

Inhibition of Nucleotide Excision Repair by Fludarabine in Normal Lymphocytes in vitro, Measured by the Alkaline Single Cell Gel Electrophoresis (Comet) Assay
por: Yamauchi, Takahiro, et al.
Publicado: (2002)

Modulation of the Effect of l‐β‐D‐Arabinofuranosylcytosine by 6‐Mercaptopurine in L1210 Cells
por: Kawai, Yasukazu, et al.
Publicado: (1994)

Close Correlation of 1‐β‐D‐Arabinofuranosylcytosine 5′‐Triphosphate, an Intracellular Active Metabolite, to the Therapeutic Efficacy of N(4)‐Behenoyl‐1‐β‐D‐arabinofuranosylcytosine Therapy for Acute Myelogenous Leukemia
por: Yamauchi, Takahiro, et al.
Publicado: (2001)

Antitumor Activity and Pharmacology of 1‐β‐D‐Arabinofuranosylcytosine‐5′‐stearylphosphate: An Orally Active Derivative of 1‐β‐D‐Arabinofuranosylcytosine
por: Kodama, Kenjiro, et al.
Publicado: (1989)

Enhancement of Ca(2+)‐dependent Endonuclease Activity in L1210 Cells during Apoptosis Induced by 1‐β‐D‐Arabinofuranosylcytosine: Possible Involvement of Activating Factor(s)
por: Takauji, Rumiko, et al.
Publicado: (1995)

Cellular pharmacology of a liposomal preparation of N4-hexadecyl-1-beta-D-arabinofuranosylcytosine, a lipophilic derivative of 1-beta-D-arabinofuranosylcytosine.
por: Horber, D. H., et al.
Publicado: (1995)

Nucleotide excision repair efficiency in quiescent human fibroblasts is modulated by circadian clock
por: Bee, Leonardo, et al.
Publicado: (2015)

Cell cycle-dependent cytotoxicity and induction of apoptosis by liposomal N4-hexadecyl-1-beta-D-arabinofuranosylcytosine.
por: Horber, D. H., et al.
Publicado: (1995)

Low density lipoprotein and liposome mediated uptake and cytotoxic effect of N(4)-octadecyl-1-β-D-arabinofuranosylcytosine in Daudi lymphoma cells
por: Koller-Lucae, S K M, et al.
Publicado: (1999)

Metabolism and Toxicity of Electroporated 1‐β‐d‐Arabinofuranosylcytosine Triphosphate in a Human Leukemia Cell Line
por: Kubota, Masaru, et al.
Publicado: (1990)

YM155 exerts potent cytotoxic activity against quiescent (G(0)/G(1)) multiple myeloma and bortezomib resistant cells via inhibition of survivin and Mcl-1
por: Ookura, Miyuki, et al.
Publicado: (2017)

TMSOTf assisted synthesis of 2’-deoxy-2’-[(18)F]fluoro-β-D-arabinofuranosylcytosine ([(18)F]FAC)
por: Gangangari, Kishore K., et al.
Publicado: (2018)

1-beta-D-arabinofuranosylcytosine (Ara-C) enhances mitochondrial activities in human leukaemic cells.
por: Muus, P., et al.
Publicado: (1991)

Haploinsufficiency for BRCA1 is associated with normal levels of DNA nucleotide excision repair in breast tissue and blood lymphocytes
por: Latimer, Jean J, et al.
Publicado: (2005)

Synergistic and antagonistic AML cell type-specific responses to 5-AZA-2’-Deoxycytidine and 1-H-D-Arabinofuranosylcytosine
por: Elmoneim, Abeer Abd, et al.
Publicado: (2014)

Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity
por: Kothandapani, Anbarasi, et al.
Publicado: (2013)

Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus
por: Souliotis, Vassilis L., et al.
Publicado: (2016)

Nucleotide excision repair: a versatile and smart toolkit: Nucleotide excision repair
por: Zhang, Xiping, et al.
Publicado: (2022)

Is the Oxidative DNA Damage Level of Human Lymphocyte Correlated with the Antioxidant Capacity of Serum or the Base Excision Repair Activity of Lymphocyte?
por: Tsai, Yi-Chih, et al.
Publicado: (2013)

Interlocking activities of DNA polymerase β in the base excision repair pathway
por: Kumar, Adarsh, et al.
Publicado: (2022)

Dexamethasone‐resistant Human Pre‐B Leukemia 697 Cell Line Evolving Elevation of Intracellular Glutathione Level: An Additional Resistance Mechanism
por: Inoue, Hitoshi, et al.
Publicado: (2002)

Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging
por: Lee, Hsin-Yi, et al.
Publicado: (2016)

Non-cytotoxic Cardiac Innate Lymphoid Cells Are a Resident and Quiescent Type 2-Commited Population
por: Bracamonte-Baran, William, et al.
Publicado: (2019)

Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins
por: Dantas, Tiago J., et al.
Publicado: (2011)

Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?
por: Kjærgaard, Sebastian, et al.
Publicado: (2020)

Pol β associated complex and base excision repair factors in mouse fibroblasts
por: Prasad, Rajendra, et al.
Publicado: (2012)

Augmentation in Chemosensitivity of Intratumor Quiescent Cells by Combined Treatment with Nicotinamide and Mild Hyperthermia
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1997)

Brefeldin A Blocks the Cytotoxicity of T Cell Receptor α/β and γ/δ Cytotoxic T Lymphocyte Clones Reacting against Human Autologous Cancer Cells
por: Wada, Yoshimasa, et al.
Publicado: (1993)

Suicidal cross-linking of PARP-1 to AP site intermediates in cells undergoing base excision repair
por: Prasad, Rajendra, et al.
Publicado: (2014)

Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast
por: Mohammad, Karamat, et al.
Publicado: (2021)

UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation
por: Pettersen, Henrik Sahlin, et al.
Publicado: (2011)

The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β
por: Harrigan, Jeanine A., et al.
Publicado: (2006)

Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair
por: Crespan, Emmanuele, et al.
Publicado: (2016)

TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair
por: Qiang, Lei, et al.
Publicado: (2015)

Oxidized nucleotide insertion by pol β confounds ligation during base excision repair
por: Çağlayan, Melike, et al.
Publicado: (2017)

Nucleotide Excision Repair in Caenorhabditis elegans
por: Lans, Hannes, et al.
Publicado: (2011)

Base excision repair and the role of MUTYH
por: Kairupan, Carla, et al.
Publicado: (2007)

Base excision DNA repair and cancer
por: Tell, Gianluca, et al.
Publicado: (2014)

DNA Oxidation and Excision Repair Pathways
por: Lee, Tae-Hee, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hd2vrj9ao8pqfui0ef2l3s3n83