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Chemoprevention of N‐Methylnitrosourea‐induced Colon Carcinogenesis by Ursodeoxycholic Acid‐5‐aminosalicylic Acid Conjugate in F344 Rats
Bile acids enhance colon carcinogenesis in animal models, whereas ursodeoxycholic acid (UDCA) suppresses it. Nonsteroid anti‐inflammatory drugs prevent colon cancer development in animals and humans. The aim of the present study was to explore the inhibitory effect of UDCA conjugate with 5‐aminosali...
Autores principales: | Narisawa, Tomio, Fukaura, Yoko, Takeba, Naomi, Nakai, Keiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926955/ https://www.ncbi.nlm.nih.gov/pubmed/11856477 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01252.x |
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