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Betulinic Acid Inhibits Growth Factor‐induced in vitro Angiogenesis via the Modulation of Mitochondrial Function in Endothelial Cells
Betulinic acid (BetA), a pentacyclic triterpene, is a selective apoptosis‐inducing agent that works directly in mitochondria. Recent study has revealed that BetA inhibits in vitro enzymatic activity of aminopeptidase N (APN, EC 3.4.11.2), which is known to play an important role in angiogenesis, but...
Autores principales: | Kwon, Ho Jeong, Shim, Joong Sup, Kim, Jin Hee, Cho, Hyun Young, Yum, Young Na, Kim, Seung Hee, Yu, Jaehoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927016/ https://www.ncbi.nlm.nih.gov/pubmed/11985792 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01273.x |
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