Hepatocyte Nuclear Factor (HNF)‐4α Induces Expression of Endothelial Fas Ligand (FasL) to Prevent Cancer Cell Transmigration: A Novel Defense Mechanism of Endothelium against Cancer Metastasis

Endothelial Fas ligand (FasL) contributes to the “immune privilege” of tissues such as testis and eye, in which apoptosis is induced in infiltrating Fas‐positive activated T cells and results in the inhibition of leukocyte extravasation. In this study, we examined the role of endothelial FasL in con...

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Detalles Bibliográficos
Autores principales: Osanai, Makoto, Chiba, Hideki, Kojima, Takashi, Fujibe, Masato, Kuwahara, Kazuhide, Kimura, Hiromichi, Satoh, Masaaki, Sawada, Norimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927027/
https://www.ncbi.nlm.nih.gov/pubmed/12036449
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01288.x

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