Duodenogastric Reflux Increases the Penetration of N‐(3)H‐Methyl‐N‐nitro‐N‐nitrosoguanidine into the Antral Mucosa of Rats: A Possible Role for Mucosal Erosions and Increased Cell Proliferation in Gastric Carcinogenesis

Duodenogastric reflux is a risk factor for gastric carcinogenesis, but the pathogenesis is not fully understood. We studied the risk of N‐methyl‐N‐nitro‐N‐nitrosoguanidine (MNNG)‐induced carcinogenesis in the antrum of rats with duodenogastric reflux. Duodenal fluid was directed into the stomach thr...

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Detalles Bibliográficos
Autores principales: Øvrebø, Kjell K., Svanes, Knut, Aase, Steinar, Grong, Ketil, Sørbye, Halfdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927029/
https://www.ncbi.nlm.nih.gov/pubmed/12036443
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01282.x

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