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Oxidative DNA Damage Induced by a Metabolite of 2–Naphthylamine, a Smoking‐related Bladder Carcinogen

2‐Naphthylamine (2‐NA), a bladder carcinogen, is contained in cigarette smoke. DNA adduct formation is thought to be a major cause of DNA damage by carcinogenic aromatic amines. We have investigated whether a metabolite of 2‐NA, 2‐nitroso‐1‐naphthol (NO‐naphthol) causes oxidative DNA damage, using (...

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Detalles Bibliográficos
Autores principales: Ohnishi, Shiho, Murata, Mariko, Kawanishi, Shosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927071/
https://www.ncbi.nlm.nih.gov/pubmed/12149138
http://dx.doi.org/10.1111/j.1349-7006.2002.tb01314.x