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Oxidative DNA Damage Induced by a Metabolite of 2–Naphthylamine, a Smoking‐related Bladder Carcinogen
2‐Naphthylamine (2‐NA), a bladder carcinogen, is contained in cigarette smoke. DNA adduct formation is thought to be a major cause of DNA damage by carcinogenic aromatic amines. We have investigated whether a metabolite of 2‐NA, 2‐nitroso‐1‐naphthol (NO‐naphthol) causes oxidative DNA damage, using (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927071/ https://www.ncbi.nlm.nih.gov/pubmed/12149138 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01314.x |