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The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens

We have demonstrated the utility of a 9–week in vivo two‐stage assay for lung cancer initiating agents, using transgenic mice carrying the human prototype c‐Ha‐ras gene (rasH2 mice) and butylhydroxytoluene (BHT) as a potent lung promoter (rasH2/BHT model). In the present study, to ascertain appropri...

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Detalles Bibliográficos
Autores principales:	Umemura, Takashi, Kodama, Yukio, Hioki, Kyoji, Nomura, Tatsuji, Nishikawa, Akiyoshi, Hirose, Masao, Kurokawa, Yuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927112/ https://www.ncbi.nlm.nih.gov/pubmed/12716462 http://dx.doi.org/10.1111/j.1349-7006.2002.tb01330.x

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