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Ras Farnesylation Inhibitor FTI‐277 Restores the E‐Cadherin/Catenin Cell Adhesion System in Human Cancer Cells and Reduces Cancer Metastasis

The E‐cadherin/catenin cell adhesion system is often down‐regulated in epithelial tumors. This is thought to play an important role in cancer invasion and metastasis, and restoration of this system may suppress metastatic spread of cancer. In this study, the effects of a Ras farnesylation inhibitor...

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Detalles Bibliográficos
Autores principales:	Nam, Jeong‐Seok, Ino, Yoshinori, Sakamoto, Michiie, Hirohashi, Setsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927130/ https://www.ncbi.nlm.nih.gov/pubmed/12359056 http://dx.doi.org/10.1111/j.1349-7006.2002.tb02479.x

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